Jason Boggs

A Novel Tankyrase Small-Molecule Inhibitor Suppresses <i>APC</i> Mutation–Driven Colorectal Tumor Growth

Ted Lau, Emily Chan, Marinella Callow et al. · Cancer Research · 2013 · 317 citations

Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index &lt; 1

Yu Zhong, Paula Katavolos, Tien‐Trung Nguyen et al. · Toxicologic Pathology · 2015 · 98 citations · Full text

Gastrointestinal Pharmacology, Gastroenterology, Pathology +16

Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton’s Tyrosine Kinase Inhibitor

Lichuan Liu, Jason Halladay, Young G. Shin et al. · Drug Metabolism and Disposition · 2011 · 73 citations

Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors

Steven T. Staben, Jianwen A. Feng, Karen S. Lyle et al. · Journal of Medicinal Chemistry · 2014 · 63 citations · Full text

Compound 17, Structure-based Methods, Kinase Inhibitors +18

The Role of Lymphatic Transport on the Systemic Bioavailability of the Bcl-2 Protein Family Inhibitors Navitoclax (ABT-263) and ABT-199

Edna F. Choo, Jason Boggs, Chunqiang Zhu et al. · Drug Metabolism and Disposition · 2013 · 60 citations