Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Jun Ishihara, Ako Ishihara, Koichi Sasaki, +15

Science Translational Medicine

ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2

Koji Chono, Kiyomitsu Katsumata, Toru Kontani, +6

Journal of Antimicrobial Chemotherapy

Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies

Kiyomitsu Katsumata, Jun Ishihara, Aslan Mansurov, +4

Science Advances

Inflammatory Lung DiseaseCollagen AffinityLung InflammationImmunologyPathology +24

ASP2397 Is a Novel Natural Compound That Exhibits Rapid and Potent Fungicidal Activity against <i>Aspergillus</i> Species through a Specific Transporter

Ikuko Nakamura, Keisuke Ohsumi, Shinobu Takeda, +5

Antimicrobial Agents and Chemotherapy

Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis

Ako Ishihara, Jun Ishihara, Elyse A. Watkins, +14

Nature Biomedical Engineering

ImmunologyImmune RegulationPathologyAlbumin–il-4 Fusion ProteinCd4 T Cell Responses +14

Synergistic activity of amenamevir (ASP2151) with nucleoside analogs against herpes simplex virus types 1 and 2 and varicella-zoster virus

Koji Chono, Kiyomitsu Katsumata, Hiroshi Suzuki, +1

Antiviral Research

Synergistic ActivityMedicineVaricella-zoster VirusPathogenesisAntiviral Drug Development +7

Suppression of Rheumatoid Arthritis by Enhanced Lymph Node Trafficking of Engineered Interleukin‐10 in Murine Models

Eiji Yuba, Erica Budina, Kiyomitsu Katsumata, +13

Arthritis & Rheumatology

Characterization of virus strains resistant to the herpes virus helicase–primase inhibitor ASP2151 (Amenamevir)

Koji Chono, Kiyomitsu Katsumata, Toru Kontani, +2

Biochemical Pharmacology

Helicase–primase Inhibitor Asp2151Molecular VirologyNeurovirologyVirus StrainsAntiviral Drug Development +8

Effect of ASP2151, a Herpesvirus Helicase-Primase Inhibitor, in a Guinea Pig Model of Genital Herpes

Kiyomitsu Katsumata, Koji Chono, Kenji Sudo, +3

Molecules

Therapeutic EffectMolecular VirologyMedicinePathogenesisViral Pathogenesis +12

A monoclonal antibody specifically reactive with Ewing's sarcoma

S. Hara, E Ishii, Shigeki Tanaka, +4

British Journal of Cancer

ImmunologyImmunoeditingPathologyImmunotherapyMedicine +1