Genichiro Ishii

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Shogo Kumagai, Yosuke Togashi, Takahiro Kamada et al. · Nature Immunology · 2020 · 785 citations

Cancer Immunosurveillance, Autoimmune Disease, T-regulatory Cell +12

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Shogo Kumagai, Shohei Koyama, Kota Itahashi et al. · Cancer Cell · 2022 · 752 citations

Cancer Immunosurveillance, Pd-1 Expression, Medicine +11

Predominant infiltration of macrophages and CD8⁺ T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer

Osamu Kawai, Genichiro Ishii, Kaoru Kubota et al. · Cancer · 2008 · 382 citations · Full text

Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial

Kiyotaka Yoh, Takashi Seto, Miyako Satouchi et al. · The Lancet Respiratory Medicine · 2016 · 292 citations

Non-small-cell Lung Cancer, Multicentre Phase 2, Medicine +7

Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction

Genichiro Ishii, Takafumi Sangai, Tatsuya Oda et al. · Biochemical and Biophysical Research Communications · 2003 · 274 citations

Malignant Blood Disorder, Myelopoiesis, Bone-marrow-derived Myofibroblasts +5