Yoshiko Takeuchi

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Shogo Kumagai, Yosuke Togashi, Takahiro Kamada et al. · Nature Immunology · 2020 · 785 citations

Cancer Immunosurveillance, Autoimmune Disease, T-regulatory Cell +12

TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Martina Molgora, Ekaterina Esaulova, William Vermi et al. · Cell · 2020 · 605 citations · Full text

Cancer Immunosurveillance, Medicine, T-regulatory Cell +10

Blockade of EGFR improves responsiveness to PD-1 blockade in <i>EGFR</i> -mutated non–small cell lung cancer

Eri Sugiyama, Yosuke Togashi, Yoshiko Takeuchi et al. · Science Immunology · 2020 · 268 citations

Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape

Yoshiko Takeuchi, Tokiyoshi Tanegashima, Eiichi Sato et al. · Science Immunology · 2021 · 124 citations

Tyrosine kinase inhibitor imatinib augments tumor immunity by depleting effector regulatory T cells

Atsushi Tanaka, Hiroyoshi Nishikawa, Shinsuke Noguchi et al. · The Journal of Experimental Medicine · 2019 · 91 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +21