Atsushi Tanaka

PD-1 ⁺ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer

Takahiro Kamada, Yosuke Togashi, Christopher Tay et al. · Proceedings of the National Academy of Sciences · 2019 · 1K citations · Full text

Life Sciences, Immunology, Oncology +17

T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development

Naganari Ohkura, Masahide Hamaguchi, Hiromasa Morikawa et al. · Immunity · 2012 · 739 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro.

Atsushi Tanaka, Chiaki Takahashi, Shoji Yamaoka et al. · Proceedings of the National Academy of Sciences · 1990 · 435 citations

Medicine, Molecular Biology, Oncology +17

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

H Zhang, J Chen, Sajid Khan Tahir et al. · Cell Death and Disease · 2015 · 429 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory

Yujiro Kidani, Wataru Nogami, Yoshiaki Yasumizu et al. · Proceedings of the National Academy of Sciences · 2022 · 204 citations · Full text

Life Sciences, Immunology, Oncology +17