Qingzhong Hu

Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17α-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure

Carsten Jagusch, Matthias Negri, Ulrike E. Hille et al. · Bioorganic & Medicinal Chemistry · 2007 · 83 citations · Full text

Molecular Pharmacology, Heterocyclic Modifications, Pharmaceutical Chemistry +12

Isopropylidene Substitution Increases Activity and Selectivity of Biphenylmethylene 4-Pyridine Type CYP17 Inhibitors

Qingzhong Hu, Lina Yin, Carsten Jagusch et al. · Journal of Medicinal Chemistry · 2010 · 73 citations · Full text

Medicinal Chemistry, Urology, Biochemistry +15

Novel CYP17 inhibitors: Synthesis, biological evaluation, structure–activity relationships and modelling of methoxy- and hydroxy-substituted methyleneimidazolyl biphenyls

Ulrike E. Hille, Qingzhong Hu, Carsten A. Vock et al. · European Journal of Medicinal Chemistry · 2009 · 70 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +13

Selective Dual Inhibitors of CYP19 and CYP11B2: Targeting Cardiovascular Diseases Hiding in the Shadow of Breast Cancer

Qingzhong Hu, Lina Yin, Rolf W. Hartmann · Journal of Medicinal Chemistry · 2012 · 68 citations · Full text

Novel Imidazol-1-ylmethyl Substituted 1,2,5,6-Tetrahydropyrrolo[3,2,1-<i>ij</i>]quinolin-4-ones as Potent and Selective CYP11B1 Inhibitors for the Treatment of Cushing’s Syndrome

Lina Yin, Simon Lucas, Frauke Maurer et al. · Journal of Medicinal Chemistry · 2012 · 64 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Cushing ’ +13