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Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17α-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure

Molecular PharmacologyHeterocyclic ModificationsPharmaceutical ChemistryBiochemistryCore StructureMedicineNatural SciencesRational Drug DesignMolecular Modelling StudiesDrug DevelopmentChemical BiologyPharmacologyMolecular ModelingEnzymatic ModificationDrug Discovery