Carsten Jagusch

Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17α-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure

Carsten Jagusch, Matthias Negri, Ulrike E. Hille et al. · Bioorganic & Medicinal Chemistry · 2007 · 83 citations · Full text

Molecular Pharmacology, Heterocyclic Modifications, Pharmaceutical Chemistry +12

Isopropylidene Substitution Increases Activity and Selectivity of Biphenylmethylene 4-Pyridine Type CYP17 Inhibitors

Qingzhong Hu, Lina Yin, Carsten Jagusch et al. · Journal of Medicinal Chemistry · 2010 · 73 citations · Full text

Medicinal Chemistry, Urology, Biochemistry +15

Synthesis, Biological Evaluation, and Molecular Modeling of Abiraterone Analogues: Novel CYP17 Inhibitors for the Treatment of Prostate Cancer

Mariano A. E. Pinto‐Bazurco Mendieta, Matthias Negri, Carsten Jagusch et al. · Journal of Medicinal Chemistry · 2008 · 69 citations · Full text

Replacement of Imidazolyl by Pyridyl in Biphenylmethylenes Results in Selective CYP17 and Dual CYP17/CYP11B1 Inhibitors for the Treatment of Prostate Cancer

Qingzhong Hu, Carsten Jagusch, Ulrike E. Hille et al. · Journal of Medicinal Chemistry · 2010 · 54 citations · Full text

Selective Cyp17, Chemoprevention Strategy, Biphenylmethylenes Results +16

An expedient synthesis of 3-acyltetramic acids of the melophlin family from α-aminoesters and immobilized Ph3PCCO

Rainer Schobert, Carsten Jagusch · Tetrahedron · 2005 · 49 citations

Combinatorial Chemistry, Immobilized Ph3pcco, Biochemistry +6