James M. Apgar

Ibrexafungerp: An orally active β-1,3-glucan synthesis inhibitor

James M. Apgar, Robert R. Wilkening, Dann L. Parker et al. · Bioorganic & Medicinal Chemistry Letters · 2020 · 48 citations

Medicine, Immunology, Pharmacotherapy +4

Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver

Eric S. Muise, Hong-Ping Guan, Jinqi Liu et al. · PLoS ONE · 2019 · 41 citations · Full text

Cardiac Muscle, Physical Activity, Muscle Function +18

Synthesis and biological evaluation of antifungal derivatives of enfumafungin as orally bioavailable inhibitors of β-1,3-glucan synthase

Brian Heasley, Gregory J. Pacofsky, Ahmed Mamai et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 33 citations

Medicinal Chemistry, β-1,3-Glucan Synthase, Antifungal Agent +10

Novel orally active inhibitors of β-1,3-glucan synthesis derived from enfumafungin

James M. Apgar, Robert R. Wilkening, Mark L. Greenlee et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 32 citations · Full text

Biochemistry, Medicine, Active Inhibitors +7

Structure–activity-relationship of amide and sulfonamide analogs of omarigliptin

Ping Chen, Dennis Feng, Xiaoxia Qian et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 18 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Natural Sciences +6