Ibrexafungerp: An orally active β-1,3-glucan synthesis inhibitor

The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation

Emily L. Larkin, Christopher Hager, Jyotsna Chandra et al. · Antimicrobial Agents and Chemotherapy · 2017 · 393 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Discovery of Novel Antifungal (1,3)-β- <scp>d</scp> -Glucan Synthase Inhibitors

Janet C. Onishi, M. Meinz, John R. Thompson et al. · Antimicrobial Agents and Chemotherapy · 2000 · 319 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

George K. Abruzzo, Amy Flattery, Christopher Gill et al. · Antimicrobial Agents and Chemotherapy · 1997 · 245 citations · Full text

Medicine, Microbiology, Pharmacology +17

Enfumafungin Derivative MK-3118 Shows Increased <i>In Vitro</i> Potency against Clinical Echinocandin-Resistant Candida Species and Aspergillus Species Isolates

Cristina Jiménez‐Ortigosa, Padmaja Paderu, Mary Motyl et al. · Antimicrobial Agents and Chemotherapy · 2013 · 121 citations · Full text

Life Sciences, Medicinal Chemistry, Microbiology +17

Asymmetric Synthesis of Protected 1,2-Amino Alcohols Using <i>tert</i>-Butanesulfinyl Aldimines and Ketimines

Tony P. Tang, Steven K. Volkman, Jonathan A. Ellman · The Journal of Organic Chemistry · 2001 · 109 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8