George K. Abruzzo - Concepedia

Author

George K. Abruzzo

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also Known As

G Abruzzo, G K Abruzzo, G. ABRUZZO, G. Abruzzo, G. K. ABRUZZO, G. K. Abruzzo, G.K. Abruzzo, GEORGE ABRUZZO, GEORGE K. ABRUZZO, George Abruzzo

Publications

4.3K

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)MSD (Spain)Merck Canada Inc. (Canada)

About

George K. Abruzzo is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, pharmacology, and microbiology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	24	35	3.1K
2	Natural Sciences	7	7	663
3	Health Sciences	6	6	989
4	Engineering	2	2	418
5	Allergy	1	1	12

George K. Abruzzo

Publications

4.2K

Citations

H-Index

Page 1

	Year	Citations
Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical <i>Candida</i> sp. Isolates S. Park, Rosemarie Kelly, Jennifer Nielsen Kahn, Antimicrobial Agents and Chemotherapy Diagnostic MycologyMicrobial PathogensRare LaboratoryPathologyMolecular Biology	2005	426
Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors Cameron Douglas, Joseph A. D'Ippolito, G.-J. Shei, Antimicrobial Agents and Chemotherapy EngineeringGlycobiologyMolecular BiologyFks1 GeneDrug Resistance	1997	336
Discovery of Novel Antifungal (1,3)-β- <scp>d</scp> -Glucan Synthase Inhibitors Janet C. Onishi, M. Meinz, John R. Thompson, Antimicrobial Agents and Chemotherapy Medicinal ChemistryBiosynthesisAntimicrobial Drug DiscoveryAntifungal AgentBiochemistry	2000	313
In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872) K Bartizal, Christopher Gill, George K. Abruzzo, Antimicrobial Agents and Chemotherapy Antifungal AgentHealth SciencesAntifungal AgentsMedicineMk-0991 Mfcs	1997	312
Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis George K. Abruzzo, Amy Flattery, Christopher Gill, Antimicrobial Agents and Chemotherapy	1997	244
Quantitative PCR Assay To Measure <i>Aspergillus fumigatus</i> Burden in a Murine Model of Disseminated Aspergillosis: Demonstration of Efficacy of Caspofungin Acetate Joel Bowman, George K. Abruzzo, Jennifer Anderson, Antimicrobial Agents and Chemotherapy Diagnostic MycologyQuantitative Pcr AssayImmunologyPathologyClinical Mycology	2001	208
Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion. Nancy H. Colburn, E. J. Wendel, George K. Abruzzo Proceedings of the National Academy of Sciences Tpa-resistant PopulationCell ProliferationCancer BiologyTumor BiologyTpa-induced Mitogenic Stimulation	1981	185
Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice George K. Abruzzo, Charles Gill, Amy Flattery, Antimicrobial Agents and Chemotherapy	2000	170
The Discovery of Enfumafungin, a Novel Antifungal Compound Produced by an Endophytic Hormonema Species Biological Activity and Taxonomy of the Producing Organisms Fernando Peláez, Angeles Cabello, Gonzalo Platas, Systematic and Applied Microbiology BiosynthesisAntifungal AgentAntifungal AgentsMedicineProducing Organisms	2000	149
Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies Martha Kurtz, George K. Abruzzo, Amy Flattery, Infection and Immunity BiologyVirulence StudiesEchinocandin-resistant MutantsBiosynthesisAntifungal Agent	1996	137

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