George K. Abruzzo

Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical <i>Candida</i> sp. Isolates

S. Park, Rosemarie Kelly, Jennifer Nielsen Kahn et al. · Antimicrobial Agents and Chemotherapy · 2005 · 426 citations · Full text

Diagnostic Mycology, Microbial Pathogens, Rare Laboratory +22

Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors

Cameron Douglas, Joseph A. D'Ippolito, G.-J. Shei et al. · Antimicrobial Agents and Chemotherapy · 1997 · 336 citations · Full text

Engineering, Glycobiology, Molecular Biology +16

Discovery of Novel Antifungal (1,3)-β- <scp>d</scp> -Glucan Synthase Inhibitors

Janet C. Onishi, M. Meinz, John R. Thompson et al. · Antimicrobial Agents and Chemotherapy · 2000 · 313 citations · Full text

Medicinal Chemistry, Biosynthesis, Antimicrobial Drug Discovery +15

In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872)

K Bartizal, Christopher Gill, George K. Abruzzo et al. · Antimicrobial Agents and Chemotherapy · 1997 · 312 citations · Full text

Antifungal Agent, Health Sciences, Antifungal Agents +12

Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

George K. Abruzzo, Amy Flattery, Christopher Gill et al. · Antimicrobial Agents and Chemotherapy · 1997 · 244 citations · Full text