Linda G. Otterson

Characterization of the Novel DNA Gyrase Inhibitor AZD0914: Low Resistance Potential and Lack of Cross-Resistance in Neisseria gonorrhoeae

Richard A. Alm, Sushmita D. Lahiri, Amy Kutschke et al. · Antimicrobial Agents and Chemotherapy · 2014 · 98 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +15

<i>In Vitro</i> Antibacterial Activity of AZD0914, a New Spiropyrimidinetrione DNA Gyrase/Topoisomerase Inhibitor with Potent Activity against Gram-Positive, Fastidious Gram-Negative, and Atypical Bacteria

Michael D. Huband, Patricia A. Bradford, Linda G. Otterson et al. · Antimicrobial Agents and Chemotherapy · 2014 · 76 citations · Full text

Life Sciences, Medicinal Chemistry, Microbiology +17

Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914)

Gregory S. Basarab, P. Doig, Vincent Galullo et al. · Journal of Medicinal Chemistry · 2015 · 71 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Antibacterial Inhibitors of Gram-Positive Thymidylate Kinase: Structure–Activity Relationships and Chiral Preference of a New Hydrophobic Binding Region

Sameer Kawatkar, Thomas A. Keating, N.B. Olivier et al. · Journal of Medicinal Chemistry · 2014 · 63 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK)

Gabriel Martínez-Botella, John Breen, J. Emmett Duffy et al. · Journal of Medicinal Chemistry · 2012 · 55 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16