Gregory S. Basarab

Crystal structure of scytalone dehydratase — a disease determinant of the rice pathogen, Magnaporthe grisea

T. Lundqvist, Janet Rice, C. Nicholas Hodge et al. · Structure · 1994 · 138 citations · Full text

Agriculture, Plant Pathology, Plant Sciences +14

UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria

Christel Brunschwig, Nina Lawrence, Dale Taylor et al. · Antimicrobial Agents and Chemotherapy · 2018 · 136 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-Based Design of Potent Inhibitors of Scytalone Dehydratase:  Displacement of a Water Molecule from the Active Site

James Chen, Simon L. Xu, Z. Wawrzak et al. · Biochemistry · 1998 · 134 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy

Brian Sherer, Kenneth G. Hull, Oluyinka Green et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 121 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +14

Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

Gregory S. Basarab, Günther Kern, John McNulty et al. · Scientific Reports · 2015 · 104 citations · Full text

Medicine, Infectious Diseases, Pharmacology +16