Osvaldo dos Santos - Concepedia

Concepedia

Author

Osvaldo dos Santos

Pearl River Community College

Also Known As

O dos Santos, O. DOS SANTOS, O. Dos Santos, Osvaldo Dos Santos, Osvaldo Santos, Osvaldo dos Santos, Osvaldo dos Santos Junior

27

Publications

1.2K

Citations

18

H-Index

34

Concepts

All Affiliations

Pearl River Community College New York University Pfizer (United States)Women's Health Research Institute Ziopharm Oncology (United States)

OD

About

Osvaldo dos Santos is an author at Pearl River Community College specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	375
2	Biochemistry	6	6	241
3	Natural Sciences	5	5	182
4	Engineering	4	4	178
5	Biomolecular Engineering	1	1	66

Osvaldo dos Santos

×

18

Publications

1.2K

Citations

18

H-Index

	Year	Citations
Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound <b>26</b> (PKI-587), a Highly Efficacious Dual Inhibitor Aranapakam M. Venkatesan, Christoph M. Dehnhardt, Efren Delos Santos, Journal of Medicinal Chemistry	2010	210
Antitumor Efficacy of PKI-587, a Highly Potent Dual PI3K/mTOR Kinase Inhibitor Robert Mallon, Larry Feldberg, Judy Lucas, Clinical Cancer Research	2011	169
Geometry-Dependent Phosphodiester Hydrolysis Catalyzed by Binuclear Copper Complexes Lei Zhu, Osvaldo dos Santos, Chi Wan Koo, Inorganic Chemistry Inorganic ChemistryBinuclear Copper ComplexesEngineeringBiochemistryPh 8.4	2003	81
Structure−Activity Relationship of 6-Methylidene Penems Bearing Tricyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors: Crystallographic Structures Show Unexpected Binding of 1,4-Thiazepine Intermediates Aranapakam M. Venkatesan, Yansong Gu, Osvaldo dos Santos, Journal of Medicinal Chemistry	2004	79
Lead Optimization of N-3-Substituted 7-Morpholinotriazolopyrimidines as Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of PKI-402 Christoph M. Dehnhardt, Aranapakam M. Venkatesan, Efren Delos Santos, Journal of Medicinal Chemistry	2009	78
PKI-179: An orally efficacious dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor Aranapakam M. Venkatesan, Zecheng Chen, Osvaldo dos Santos, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologySignal TransductionSignaling Pathway/Mammalian TargetMedicine	2010	71
2,4-Diamino-quinazolines as inhibitors of β-catenin/Tcf-4 pathway: Potential treatment for colorectal cancer Zecheng Chen, Aranapakam M. Venkatesan, Christoph M. Dehnhardt, Bioorganic & Medicinal Chemistry Letters Tumor BiologyMedicinePharmacologyPathologyColorectal Cancer	2009	69
5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of β-lactamases Aranapakam M. Venkatesan, Atul Agarwal, Takao Abé, Bioorganic & Medicinal Chemistry Medicinal ChemistryAntimicrobial Drug DiscoveryMedicineDrug DiscoveryBroad-spectrum Inhibitors	2007	66
Antitumor Efficacy Profile of PKI-402, a Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor Robert Mallon, Irwin Hollander, Larry Feldberg, Molecular Cancer Therapeutics	2010	59
Sulfonation and anticoagulant activity of botryosphaeran from Botryosphaeria rhodina MAMB-05 grown on fructose Simone Ferreira Mendes, Osvaldo dos Santos, Aneli M. Barbosa, International Journal of Biological Macromolecules Industrial MycologyMamb-05 GrownBiosynthesisEngineeringBiochemistry	2009	54

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