Robert Mallon

Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound <b>26</b> (PKI-587), a Highly Efficacious Dual Inhibitor

Aranapakam M. Venkatesan, Christoph M. Dehnhardt, Efren Delos Santos et al. · Journal of Medicinal Chemistry · 2010 · 212 citations · Full text

Medicine, Oncology, Pharmacology +14

Antitumor Efficacy of PKI-587, a Highly Potent Dual PI3K/mTOR Kinase Inhibitor

Robert Mallon, Larry Feldberg, Judy Lucas et al. · Clinical Cancer Research · 2011 · 170 citations · Full text

Medicine, Oncology, Pharmacology +17

Liphagal, a Selective Inhibitor of PI3 Kinase α Isolated from the Sponge <i>Aka </i><i>c</i><i>oralliphaga</i>:  Structure Elucidation and Biomimetic Synthesis

Frédéric Marion, David E. Williams, Brian O. Patrick et al. · Organic Letters · 2005 · 155 citations

Natural Sciences, Biochemistry, Medicinal Chemistry +16

Aldisine Alkaloids from the Philippine Sponge <i>Stylissa </i><i>m</i><i>assa</i> Are Potent Inhibitors of Mitogen-Activated Protein Kinase Kinase-1 (MEK-1)

Deniz Taşdemir, Robert Mallon, Michael Greenstein et al. · Journal of Medicinal Chemistry · 2001 · 151 citations · Full text

Medicine, Oncology, Pharmacology +13

Lead Optimization of N-3-Substituted 7-Morpholinotriazolopyrimidines as Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of PKI-402

Christoph M. Dehnhardt, Aranapakam M. Venkatesan, Efren Delos Santos et al. · Journal of Medicinal Chemistry · 2009 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16