Inge Bruggeman

MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

Yves Dondelinger, Wim Declercq, Sylvie Montessuit et al. · Cell Reports · 2014 · 797 citations · Full text

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

Yves Dondelinger, Tom Delanghe, Diego Rojas‐Rivera et al. · Nature Cell Biology · 2017 · 201 citations

Mk2 Phosphorylation, Signal Transduction, Cell Regulation +6

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten Remijsen, Vera Goossens, Sasker Grootjans et al. · Cell Death and Disease · 2014 · 192 citations · Full text

Mitophagy, Apoptosis, Immunology +20

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice

Tom Vanden Berghe, Paco Hulpiau, Liesbet Martens et al. · Immunity · 2015 · 167 citations · Full text

Knockout Mouse, Allelic Variant, Developmental Biology +8

Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis

Kathrin Weber, Ria Roelandt, Inge Bruggeman et al. · Communications Biology · 2018 · 161 citations · Full text

Cytosolic Necrosome Formation, Apoptosis, Immunology +19