Franz von Nussbaum

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction

R.C. Hillig, Brice Sautier, Jens Schroeder et al. · Proceedings of the National Academy of Sciences · 2019 · 363 citations · Full text

The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage–Inducing or Repair–Compromising Therapies in Preclinical Cancer Models

Antje M. Wengner, Gerhard Siemeister, Ulrich Lücking et al. · Molecular Cancer Therapeutics · 2019 · 200 citations

Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer

Ulrich Lücking, Arne Scholz, Philip Lienau et al. · ChemMedChem · 2017 · 176 citations · Full text

A Rapid Total Synthesis of Spirotryprostatin B: Proof of Its Relative and Absolute Stereochemistry

Franz von Nussbaum, Samuel J. Danishefsky · Angewandte Chemie International Edition · 2000 · 117 citations

Bioorganic Chemistry, Molecular Biology, Chemical Biology +17

Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity

Antje M. Wengner, Gerhard Siemeister, Marcus Koppitz et al. · Molecular Cancer Therapeutics · 2016 · 117 citations · Full text

Oncology, Medicine, Potent Antitumor Activity +14