R.C. Hillig

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

John K. Eaton, Laura Furst, Richard A. Ruberto et al. · Nature Chemical Biology · 2020 · 472 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +6

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction

R.C. Hillig, Brice Sautier, Jens Schroeder et al. · Proceedings of the National Academy of Sciences · 2019 · 379 citations · Full text

Medicine, Molecular Biology, Oncology +17

The complex of Arl2‐GTP and PDEδ: from structure to function

Michael Hanzal‐Bayer, Louis Renault, Pietro Roversi et al. · The EMBO Journal · 2002 · 224 citations · Full text

Life Sciences, Biology, Molecular Biology +7

Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides

Khyati Kapoor, Janet Finer-Moore, Bjørn Panyella Pedersen et al. · Proceedings of the National Academy of Sciences · 2016 · 215 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

Stefan Pusch, Sonja Krausert, Viktoria Fischer et al. · Acta Neuropathologica · 2017 · 175 citations

Medicine, Oncology, Pharmacology +10