Anja Capell

ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import

Dorothee Dormann, Ramona Rodde, Dieter Edbauer et al. · The EMBO Journal · 2010 · 836 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway

Christian Haass, Cynthia A. Lemere, Anja Capell et al. · Nature Medicine · 1995 · 581 citations

Life Sciences, Molecular Biology, Neurology +17

Presenilin‐dependent γ‐secretase processing of β‐amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

Magdalena Sastre, Harald Steiner, Klaus Fuchs et al. · EMBO Reports · 2001 · 469 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue

Taisuke Tomita, Kei Maruyama, Takaomi C. Saido et al. · Proceedings of the National Academy of Sciences · 1997 · 385 citations

Life Sciences, Genetics, Molecular Biology +16

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Marc Suárez‐Calvet, Estrella Morenas‐Rodríguez, Gernot Kleinberger et al. · Molecular Neurodegeneration · 2019 · 380 citations · Full text

Life Sciences, Neurology, Neuroscience +17