Magdalena Sastre

Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1–42 levels in APPV717I transgenic mice

Michael T. Heneka, Magdalena Sastre, Lucia Dumitrescu‐Ozimek et al. · Brain · 2005 · 550 citations · Full text

Acute Treatment, Immune Regulation, Immunology +22

Presenilin‐dependent γ‐secretase processing of β‐amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

Magdalena Sastre, Harald Steiner, Klaus Fuchs et al. · EMBO Reports · 2001 · 468 citations · Full text

Protein Secretion, Protein Function, Protein Expression +9

Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson’s disease

Heiko Braak, Magdalena Sastre, Kelly Del Tredici · Acta Neuropathologica · 2007 · 427 citations

Neurodegenerative Diseases, Neurobiology Of Disease, Synaptic Transmission +15

Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NFκB and iNOS activation

Thomas Dehmer, Michael T. Heneka, Magdalena Sastre et al. · Journal of Neurochemistry · 2003 · 379 citations · Full text

Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ

Magdalena Sastre, Ilse Dewachter, Nenad Bogdanović et al. · Proceedings of the National Academy of Sciences · 2006 · 372 citations · Full text