Alfred Zimmerlin

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

Vito Guagnano, Pascal Furet, Carsten Spanka et al. · Journal of Medicinal Chemistry · 2011 · 484 citations · Full text

Pharmaceutical Chemistry, Tumor Biology, Medicinal Chemistry +19

Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Daniela Angst, F. Gessier, Philipp Janser et al. · Journal of Medicinal Chemistry · 2020 · 149 citations · Full text

Metabolic Soft Spot Identification and Compound Optimization in Early Discovery Phases Using MetaSite and LC-MS/MS Validation

Markus Trunzer, Bernard Faller, Alfred Zimmerlin · Journal of Medicinal Chemistry · 2008 · 116 citations

Molecular identification and expression of the peroxidase responsible for the oxidative burst in French bean (Phaseolus vulgaris L.) and related members of the gene family

Kristopher A. Blee, S Jupe, Gaëlle Richard et al. · Plant Molecular Biology · 2001 · 94 citations

Tissue and subcellular immunolocalisation of enzymes of lignin synthesis in differentiating and wounded hypocotyl tissue of French bean (Phaseolus vulgaris L.)

ColinG. Smith, MatthewW. Rodgers, Alfred Zimmerlin et al. · Planta · 1994 · 93 citations

Plant Physiology, Subcellular Immunolocalisation, Biomanufacturing +10