F. Gessier

Oxysterols direct immune cell migration via EBI2

Sébastien Hannedouche, Juan Zhang, Tangsheng Yi et al. · Nature · 2011 · 477 citations

Life Sciences, Cell Biology, Immunology +11

Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors

Philipp Holzer, Keiichi Masuya, Pascal Furet et al. · Journal of Medicinal Chemistry · 2015 · 206 citations · Full text

Medicine, Oncology, Pharmacology +15

Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Daniela Angst, F. Gessier, Philipp Janser et al. · Journal of Medicinal Chemistry · 2020 · 162 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Probing the Proteolytic Stability of β‐Peptides Containing α‐Fluoro‐ and α‐Hydroxy‐β‐Amino Acids

David Höök, F. Gessier, Christian Noti et al. · ChemBioChem · 2004 · 131 citations · Full text

Life Sciences, Biochemistry, Enzymology +16

A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097

Sébastien Jeay, Swann Gaulis, Stéphane Ferretti et al. · eLife · 2015 · 87 citations · Full text

Medicine, Cancer Biology, Oncology +17