Concepedia

Author

Markus Trunzer

Novartis (Switzerland)ORCID

Also Known As

Markus Trunzer

15

Publications

379

Citations

10

H-Index

27

Concepts

All Affiliations

Novartis (Switzerland)Novartis Institutes for BioMedical ResearchNovartis (United States)
MT

About

Markus Trunzer is an author at Novartis (Switzerland) specializing in medicine, bioanalysis, and medicinal chemistry.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

59

2

Natural Sciences

2

2

32

3

Biochemistry

2

2

32

4

Health Sciences

1

1

27

5

Cell Biology

1

1

27

Markus Trunzer

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10

Publications

364

Citations

10

H-Index

YearCitations

Metabolic Soft Spot Identification and Compound Optimization in Early Discovery Phases Using MetaSite and LC-MS/MS Validation

Markus Trunzer, Bernard Faller, Alfred Zimmerlin

Journal of Medicinal Chemistry

2008

116

CYP3A Time-Dependent Inhibition Risk Assessment Validated with 400 Reference Drugs

Alfred Zimmerlin, Markus Trunzer, Bernard Faller

Drug Metabolism and Disposition

2011

90

Multispecies Machine Learning Predictions of In Vitro Intrinsic Clearance with Uncertainty Quantification Analyses

Raquel Rodríguez-Pérez, Markus Trunzer, Nadine Schneider,

Molecular Pharmaceutics

2022

34

NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

Kenji Namoto, Clara Baader, Vanessa Orsini,

Cell stem cell

2024

27

Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome

Angela Mackay, Juraj Velcicky, Nina Gommermann,

Journal of Medicinal Chemistry

2024

25

An Integrated Approach for Identification and Target Validation of Antifungal Compounds Active against Erg11p

Dominic Hoepfner, Shantanu Karkare, Stephen B. Helliwell,

Antimicrobial Agents and Chemotherapy

2012

21

Two‐dimensional liquid chromatography/mass spectrometry set‐up for structural elucidation of metabolites in complex biological matrices

Michael Kiffe, Daniel Graf, Markus Trunzer

Rapid Communications in Mass Spectrometry

2007

15

Comparison of a two‐dimensional liquid chromatography/mass spectrometry approach with a chip‐based nanoelectrospray device for structural elucidation of metabolites in a human ADME study using a quadrupole time‐of‐flight mass spectrometer

Markus Trunzer, Daniel Graf, Michael Kiffe

Rapid Communications in Mass Spectrometry

2007

13

Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition

Andrin Fluetsch, Markus Trunzer, Grégori Gerebtzoff,

Chemical Research in Toxicology

2024

12

Evaluation of relative MS response factors of drug metabolites for semi‐quantitative assessment of chemical liabilities in drug discovery

Joachim Blanz, Gareth Williams, Jérôme Dayer,

Journal of Mass Spectrometry

2017

11

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