Angela Mackay

Roles of key active-site residues in flavocytochrome P450 BM3

Michael A. Noble, Caroline S. Miles, Stephen K. Chapman et al. · Biochemical Journal · 1999 · 260 citations · Full text

Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition

Carien Dekker, Henri Mattes, Michael Wright et al. · Journal of Molecular Biology · 2021 · 149 citations

Crystal Structure, Anti-inflammatory, Signal Transduction +9

Stereocontrolled Total Synthesis of (−)‐Aurisides A and B

Ian Paterson, Gordon J. Florence, Annekatrin C. Heimann et al. · Angewandte Chemie International Edition · 2005 · 70 citations · Full text

Marine Biotechnology, Glycosylation, Biochemistry +13

Discovery of (7<i>R</i>)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6<i>H</i>-indolo[1,2-<i>e</i>][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase

Frank Narjes, Benedetta Crescenzi, Marco Ferrara et al. · Journal of Medicinal Chemistry · 2010 · 65 citations · Full text

Roles of key active-site residues in flavocytochrome P450 BM3

Michael A. Noble, Caroline S. Miles, Stephen K. Chapman et al. · Biochemical Journal · 1999 · 63 citations

Key Active-site Residues, Protein Function, Biochemistry +14