Carsten Spanka

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

Vito Guagnano, Pascal Furet, Carsten Spanka et al. · Journal of Medicinal Chemistry · 2011 · 484 citations · Full text

Pharmaceutical Chemistry, Tumor Biology, Medicinal Chemistry +19

Oxysterols direct immune cell migration via EBI2

Sébastien Hannedouche, Juan Zhang, Tangsheng Yi et al. · Nature · 2011 · 460 citations

Cell Trafficking, Immunology, Redox Biology +6

A segmented flow platform for on-demand medicinal chemistry and compound synthesis in oscillating droplets

Ye‐Jin Hwang, Connor W. Coley, Milad Abolhasani et al. · Chemical Communications · 2017 · 89 citations

Engineering, Liquid-liquid Flow, Fluid Mechanics +21

<i>N</i>-Sulfonylanthranilic Acid Derivatives as Allosteric Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase

Zheng Yin, Yen‐Liang Chen, Ravinder Reddy Kondreddi et al. · Journal of Medicinal Chemistry · 2009 · 63 citations · Full text

Bioorganic Chemistry, Viral Polymerase Structure, Allosteric Inhibitors +18

Solid-Phase Rhodium Carbenoid Reactions:  An N−H Insertion Route to a Diverse Series of Oxazoles

Bruce Clapham, Carsten Spanka, Kim D. Janda · Organic Letters · 2001 · 60 citations

Chemical Engineering, Solid-phase Synthesis, Engineering +14