Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus

P. Erbel, Nikolaus Schiering, A. D’Arcy, +7

Nature Structural & Molecular Biology

Virus StructureViral ReplicationPathogenesisMolecular BiologyVirology +8

An adenosine nucleoside inhibitor of dengue virus

Zheng Yin, Yen‐Liang Chen, Wouter Schul, +30

Proceedings of the National Academy of Sciences

Dengue VirusMolecular VirologyMedicineImmunologyAntiviral Therapy +7

Widespread Choroidal Insufficiency in Primary Open-Angle Glaucoma

Zheng Yin, Vaegan, Tom J. Millar, +2

Journal of Glaucoma

Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase

Siew Pheng Lim, Louis Sebastian Sonntag, Christian G. Noble, +18

Journal of Biological Chemistry

Peptide inhibitors of dengue virus NS3 protease. Part 1: Warhead

Zheng Yin, Sejal Patel, Weiling Wang, +11

Bioorganic & Medicinal Chemistry Letters

ImmunologyAntiviral Drug DevelopmentVirologyAntiviral DrugViral Structural Protein +3

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors

Zheng Yin, Sejal Patel, Weiling Wang, +12

Bioorganic & Medicinal Chemistry Letters

Antiviral CompoundBiochemistryAntiviral Drug DevelopmentSar StudyVirology +7

Discovery of a Non-Peptidic Inhibitor of West Nile Virus NS3 Protease by High-Throughput Docking

Dariusz Ekonomiuk, Xun‐Cheng Su, Kiyoshi Ozawa, +9

PLoS neglected tropical diseases

Inhibition of Dengue Virus Polymerase by Blocking of the RNA Tunnel

Pornwaratt Niyomrattanakit, Yen‐Liang Chen, Hongping Dong, +10

Journal of Virology

Viral ReplicationDengue VirusMolecular BiologyRna TunnelAntiviral Drug +16

Tripeptide inhibitors of dengue and West Nile virus NS2B–NS3 protease

Andreas Schüller, Zheng Yin, C. S. Brian Chia, +6

Antiviral Research

MedicineTripeptide InhibitorsAntiviral Drug DevelopmentVirologyAntiviral Drug +4

Peptide Inhibitors of West Nile NS3 Protease:  SAR Study of Tetrapeptide Aldehyde Inhibitors

John E. Knox, Ngai Ling, Zheng Yin, +11

Journal of Medicinal Chemistry

Crystal StructureProtein AssemblyBiomolecular Structure PredictionMolecular BiologyViral Structural Protein +17