Publication | Closed Access
A segmented flow platform for on-demand medicinal chemistry and compound synthesis in oscillating droplets
89
Citations
26
References
2017
Year
EngineeringLiquid-liquid FlowFluid MechanicsBiomedical EngineeringChemistryCompatible ChemistriesChemical EngineeringSegmented Flow PlatformPharmaceutical TechnologyMicrofluidicsFlow ChemistryDisperse FlowFlow SynthesisProcess Systems EngineeringMultiphase FlowMultiphase ProcessingOn-demand Medicinal ChemistryProcess IntensificationFlow Chemistry PlatformReaction EngineeringMicroemulsionChemical KineticsReaction VolumeCompound Synthesis
We report an automated flow chemistry platform that can efficiently perform a wide range of chemistries, including single/multi-phase and single/multi-step, with a reaction volume of just 14 μL. The breadth of compatible chemistries is successfully demonstrated and the desired products are characterized, isolated, and collected online by preparative HPLC/MS/ELSD.
| Year | Citations | |
|---|---|---|
Page 1
Page 1