A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

Cristina Escribano‐Diaz, Alexandre Orthwein, Amélie Fradet‐Turcotte, +9

Molecular Cell

ChromatinGenome InstabilityCell RegulationChromatin RemodelingMolecular Regulation +6

A Genetic Map of the Response to DNA Damage in Human Cells

Michele Olivieri, Tiffany Cho, Alejandro Álvarez-Quilón, +26

Cell

ChromatinGenome InstabilityGenetic AnalysisDna DamageHuman Cell +10

RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability

Dongyi Xu, Rong Guo, Alexandra Sobeck, +7

Genes & Development

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

Mengtan Xing, Mingrui Yang, Wei Huo, +16

Nature Communications

Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation

Dongyi Xu, Weiping Shen, Rong Guo, +21

Nature Neuroscience

Molecular NeuroscienceSynapse FormationFragile X SpectrumMolecular BiologyMedicine +2

CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair

Tanu Shenoy, Gunther Boysen, M.Y. Wang, +23

Annals of Oncology

Rif1 provides a new DNA‐binding interface for the Bloom syndrome complex to maintain normal replication

Dongyi Xu, Parameswary A. Muniandy, Elisabetta Leo, +17

The EMBO Journal

An OB-fold complex controls the repair pathways for DNA double-strand breaks

Shengxian Gao, Sumin Feng, Shaokai Ning, +8

Nature Communications

RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals

Muzammil Ahmad, Yutong Xue, Seung Kyu Lee, +18

Nucleic Acids Research

BiologyDna TopoisomerasesTranscriptional RegulationSystems BiologyNatural Sciences +11

53BP1 and BRCA1 control pathway choice for stalled replication restart

Yixi Xu, Shaokai Ning, Wei Zheng, +5

eLife

ChromatinGenome InstabilityStalled Replication RestartReplication ForksCell Regulation +9