Amélie Fradet‐Turcotte

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

Traver Hart, Megha Chandrashekhar, Michael Aregger et al. · Cell · 2015 · 1.7K citations · Full text

Genotype-specific Cancer Liabilities, Engineering, Genetics +9

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

Cristina Escribano‐Diaz, Alexandre Orthwein, Amélie Fradet‐Turcotte et al. · Molecular Cell · 2013 · 891 citations · Full text

Chromatin, Genome Instability, Cell Regulation +8

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

Amélie Fradet‐Turcotte, Marella D. Canny, Cristina Escribano‐Diaz et al. · Nature · 2013 · 670 citations

Chromatin, Genome Instability, Chromatin Remodeling +8

Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions

Alexandre Orthwein, Amélie Fradet‐Turcotte, Sylvie M. Noordermeer et al. · Science · 2014 · 318 citations

Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency

Marella D. Canny, Nathalie Moatti, Leo C. K. Wan et al. · Nature Biotechnology · 2017 · 286 citations · Full text

Chromatin, Genome Instability, Genetics +7