Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation

Natural RNA circles function as efficient microRNA sponges

Thomas B. Hansen, Trine I. Jensen, Bettina Hjelm Clausen et al. · Nature · 2013 · 8.3K citations

Biology, Systems Biology, Natural Sciences +6

Circular RNAs are a large class of animal RNAs with regulatory potency

Sebastian Memczak, Marvin Jens, Antigoni Elefsinioti et al. · Nature · 2013 · 8.3K citations

Biology, Circular Rnas, Natural Sciences +8

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

Annemieke J.M.H. Verkerk, Maura Pieretti, James S. Sutcliffe et al. · Cell · 1991 · 3.5K citations

Breakpoint Cluster Region, Fragile X Syndrome, Mendelian Disorder +11

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

Jennifer C. Darnell, Sarah J. Van Driesche, Chaolin Zhang et al. · Cell · 2011 · 2.1K citations · Full text

Molecular Neuroscience, Developmental Biology, Syndromic Autism +9

Genome-wide association study identifies five new schizophrenia loci

Nature Genetics · 2011 · 1.9K citations · Full text

Genome-wide Association Study, Psychiatry, Genetics +6