Frédéric Cumin

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M. Wood, Jürgen Maibaum, Joseph Rahuel et al. · Biochemical and Biophysical Research Communications · 2003 · 503 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin

Joseph Rahuel, Vittorio Rasetti, Jürgen Maibaum et al. · Chemistry & Biology · 2000 · 321 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Analysis by immunocytochemistry and in situ hybridization of renin and its mRNA in kidney, testis, adrenal, and pituitary of the rat.

Christian F. Deschepper, Synthia H. Mellon, Frédéric Cumin et al. · Proceedings of the National Academy of Sciences · 1986 · 253 citations

Life Sciences, Cell Biology, Endocrinology +9

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Anna Schubart, Karen Anderson, Nello Mainolfi et al. · Proceedings of the National Academy of Sciences · 2019 · 216 citations · Full text

Medicine, Nephrology, Pharmacology +17

Inhibition of Food Intake by Neuropeptide Y Y5 Receptor Antisense Oligodeoxynucleotides

Andrea O. Schaffhauser, Alain Stricker‐Krongrad, L. Brunner et al. · Diabetes · 1997 · 176 citations

Medicine, Neuroscience, Pharmacology +10