Robert J. Lake

MAML1, a human homologue of Drosophila Mastermind, is a transcriptional co-activator for NOTCH receptors

Lizi Wu, Jon C. Aster, Stephen C. Blacklow et al. · Nature Genetics · 2000 · 578 citations

Transcriptional Regulation, Systems Biology, Developmental Biology +9

DOCK4, a GTPase Activator, Is Disrupted during Tumorigenesis

Vijay Yajnik, Charles Paulding, Raffaella Sordella et al. · Cell · 2003 · 228 citations · Full text

Medicine, Tumor Suppressor, Cancer Biology +3

AI is a viable alternative to high throughput screening: a 318-target study

Daniel A. Lawrence, David J. Hosfield, Frederick S. Vizeacoumar et al. · Scientific Reports · 2024 · 107 citations · Full text

Artificial Intelligence, Engineering, Machine Learning +26

UV-Induced Association of the CSB Remodeling Protein with Chromatin Requires ATP-Dependent Relief of N-Terminal Autorepression

Robert J. Lake, Anastasia Geyko, Girish Hemashettar et al. · Molecular Cell · 2010 · 100 citations · Full text

Chromatin, Chromatin Structure, Chromatin Remodeling +11

RBPJ, the Major Transcriptional Effector of Notch Signaling, Remains Associated with Chromatin throughout Mitosis, Suggesting a Role in Mitotic Bookmarking

Robert J. Lake, Pei-Fang Tsai, Inchan Choi et al. · PLoS Genetics · 2014 · 90 citations · Full text

Chromatin, Transcriptional Regulation, Major Transcriptional Effector +13