Charles Paulding

Epigenetic Modification of the <i>FMR1</i> Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056

Sébastien Jacquemont, Aurore Curie, Vincent des Portes et al. · Science Translational Medicine · 2011 · 610 citations

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

Jonathan B. Singer, Steve Lewitzky, Elisabeth Leroy et al. · Nature Genetics · 2010 · 383 citations

Genome-wide Association Study, Allelic Variant, Hepatology +13

The Wilms Tumor Suppressor WT1 Encodes a Transcriptional Activator of amphiregulin

Sean Bong Lee, Karen Huang, Rachel Palmer et al. · Cell · 1999 · 307 citations · Full text

Transcriptional Regulation, Gene Regulation, Transcriptional Activator +6

Common and rare variant associations with clonal haematopoiesis phenotypes

Michael D. Kessler, Amy Damask, Sean O’Keeffe et al. · Nature · 2022 · 281 citations · Full text

Allelic Variant, Rare Variant Associations, Hematology +2

Sequencing of 640,000 exomes identifies <i>GPR75</i> variants associated with protection from obesity

Parsa Akbari, Ankit Gilani, Olukayode Sosina et al. · Science · 2021 · 259 citations · Full text