UV-Induced Association of the CSB Remodeling Protein with Chromatin Requires ATP-Dependent Relief of N-Terminal Autorepression

Robert J. Lake, Anastasia Geyko, Girish Hemashettar, +2

Molecular Cell

ChromatinChromatin StructureChromatin RemodelingNatural SciencesUv-induced Association +9

An Anti-HIV-1 V3 Loop Antibody Fully Protects Cross-Clade and Elicits T-Cell Immunity in Macaques Mucosally Challenged with an R5 Clade C SHIV

Jennifer Watkins, Nagadenahalli B. Siddappa, Samir K. Lakhashe, +18

PLoS ONE

Elicits T-cell ImmunityImmunologyViral PathogenesisImmunotherapyViral Evolution +14

Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: Complete protection of rhesus monkeys from mucosal SHIV challenge

Anton M. Sholukh, Jennifer Watkins, Hemant K. Vyas, +15

Vaccine

Mucosal VaccinationComplete ProtectionMedicineHuman RetrovirusImmunology +8

Prime–boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: Efficacy against repeated mucosal R5 clade C SHIV challenges

Samir K. Lakhashe, Vijayakumar Velu, Gaia Sciaranghella, +20

Vaccine

VaccinationVaccine ResearchImmunologyAntiviral ResponseVirology +7

Schistosoma mansoni Enhances Host Susceptibility to Mucosal but Not Intravenous Challenge by R5 Clade C SHIV

Nagadenahalli B. Siddappa, Girish Hemashettar, Vivekanandan Shanmuganathan, +6

PLoS neglected tropical diseases

Vaccination against Heterologous R5 Clade C SHIV: Prevention of Infection and Correlates of Protection

Samir K. Lakhashe, Wendy Wang, Nagadenahalli B. Siddappa, +11

PLoS ONE

ImmunologyStep TrialPeak ViremiaCross-protectionVaccine Target +15

Development of a tier 1 R5 clade C simian–human immunodeficiency virus as a tool to test neutralizing antibody‐based immunoprophylaxis

Nagadenahalli B. Siddappa, Girish Hemashettar, Yin Ling Wong, +8

Journal of Medical Primatology

Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose

Anton M. Sholukh, Nagadenahalli B. Siddappa, Vivekanandan Shanmuganathan, +22

Retrovirology

Isolation of Monoclonal Antibodies with Predetermined Conformational Epitope Specificity

Anton M. Sholukh, Muhammad M. Mukhtar, Michael Humbert, +11

PLoS ONE

Autoimmune DiseaseImmunologyAntiviral ResponseEpitope MimeticsVirology +12