MAML1, a human homologue of Drosophila Mastermind, is a transcriptional co-activator for NOTCH receptors

Lizi Wu, Jon C. Aster, Stephen C. Blacklow, +3

Nature Genetics

Transcriptional RegulationSystems BiologyDevelopmental BiologySignal TransductionDevelopmental Genetics +7

t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway

Giovanni Tonon, Sanjay Modi, Lizi Wu, +9

Nature Genetics

Tumor BiologyMucoepidermoid CarcinomaOncogenic AgentMedicinePathology +6

Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications

D. Gupta, SP Treon, Yoshihito Shima, +14

Leukemia

Marrow Stromal CellsCell TherapyAngiogenesisImmunologyHematology +6

Immobilization of Notch ligand, Delta-1, is required for induction of Notch signaling

Barbara Varnum‐Finney, Lizi Wu, Monica Yu, +5

Journal of Cell Science

CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications

Y-T Tai, Yosef Landesman, Chirag Acharya, +21

Leukemia

Tumor BiologyOncologyBone Morphogenic ProteinMedicineImpairs Osteoclastogenesis +8

Identification of a Family of Mastermind-Like Transcriptional Coactivators for Mammalian Notch Receptors

Lizi Wu, Tao Sun, Karla Kobayashi, +2

Molecular and Cellular Biology

Molecular RegulationGene Regulatory NetworkTranscriptional RegulationMastermind-like Transcriptional CoactivatorsSignaling Pathway +14

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

Jianhui Ma, Yan Meng, David J. Kwiatkowski, +24

Journal of Clinical Investigation

Enhanced Notch SignalingMolecular RegulationImmunologyCell DifferentiationTumor Biology +16

Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response

Fang Yu, Jiangbo Wei, Xiaolong Cui, +6

Nucleic Acids Research

cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth

Zirong Chen, Jian‐Liang Li, Shuibin Lin, +12

Journal of Clinical Investigation

Lkb1-inactivated NsclcCancer ResearchTranscriptional RegulationMedicineCancer Growth +13

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

Huangxuan Shen, Abigail McElhinny, Yang Cao, +5

Genes & Development

Maml ProteinsNormal MyogenesisCellular PhysiologyTranscriptional RegulationNotch Coactivator +15