Robert A. Egnatchik

A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth

John C. Schell, Kristofor A. Olson, Lei Jiang et al. · Molecular Cell · 2014 · 374 citations · Full text

Systems Biology, Mitochondrial Pyruvate Carrier, Mitochondrial Function +10

Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth

Lingtao Jin, Dan Li, Gina N. Alesi et al. · Cancer Cell · 2015 · 353 citations · Full text

Reductive Stress, Redox Signaling, Biochemistry +12

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

Takla Griss, Emma E. Vincent, Robert A. Egnatchik et al. · PLoS Biology · 2015 · 210 citations · Full text

Tumor Biology, Mitochondrial-dependent Biosynthesis, Vitro Metformin +14

Palmitate-induced Activation of Mitochondrial Metabolism Promotes Oxidative Stress and Apoptosis in H4IIEC3 Rat Hepatocytes

Robert A. Egnatchik, Alexandra K. Leamy, Yasushi Noguchi et al. · Metabolism · 2013 · 159 citations · Full text

Biochemistry, Mitochondrial Function, Lipid Peroxidation +11

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload

Robert A. Egnatchik, Alexandra K. Leamy, David A. Jacobson et al. · Molecular Metabolism · 2014 · 149 citations · Full text