Katrina A. Bollinger

Design and Synthesis of <i>N</i>-Aryl Phenoxyethoxy Pyridinones as Highly Selective and CNS Penetrant mGlu₃ NAMs

Julie L. Engers, Katrina A. Bollinger, Rebecca L. Weiner et al. · ACS Medicinal Chemistry Letters · 2017 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Design and Synthesis of mGlu₂NAMs with Improved Potency and CNS Penetration Based on a Truncated Picolinamide Core

Katrina A. Bollinger, Andrew S. Felts, Christopher J. Brassard et al. · ACS Medicinal Chemistry Letters · 2017 · 38 citations · Full text

Pharmacy, Neuroscience, Pharmacology +12

Discovery of VU6005649, a CNS Penetrant mGlu_7/8 Receptor PAM Derived from a Series of Pyrazolo[1,5-<i>a</i>]pyrimidines

Masahito Abe, Mabel Seto, Rocco G. Gogliotti et al. · ACS Medicinal Chemistry Letters · 2017 · 35 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core

Michael R. Wood, Meredith J. Noetzel, Julie L. Engers et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery of imidazo[1,2-a]-, [1,2,4]triazolo[4,3-a]-, and [1,2,4]triazolo[1,5-a]pyridine-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5

Andrew S. Felts, Alice L. Rodriguez, Ryan D. Morrison et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 10 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12