Andrew S. Felts

Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships

Karen J. Gregory, Meredith J. Noetzel, Jerri M. Rook et al. · Molecular Pharmacology · 2012 · 92 citations · Full text

The 2′-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor

Anna L. Blobaum, Md. Jashim Uddin, Andrew S. Felts et al. · ACS Medicinal Chemistry Letters · 2013 · 70 citations · Full text

Molecular Basis of the Time-Dependent Inhibition of Cyclooxygenases by Indomethacin

Jeffery J. Prusakiewicz, Andrew S. Felts, Bonnie S. Mackenzie et al. · Biochemistry · 2004 · 60 citations

Molecular Pharmacology, Medicinal Chemistry, Aldehyde Dehydrogenase +13

Discovery of (<i>R</i>)-(2-Fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-Hydroxypiperidin-1-yl)methanone (ML337), An mGlu₃ Selective and CNS Penetrant Negative Allosteric Modulator (NAM)

Cody J. Wenthur, Ryan D. Morrison, Andrew S. Felts et al. · Journal of Medicinal Chemistry · 2013 · 55 citations · Full text

Chemical Biology, Pharmaceutical Chemistry, Translational Pharmacology +17

Discovery of 2‐(2‐Benzoxazoyl amino)‐4‐Aryl‐5‐Cyanopyrimidine as Negative Allosteric Modulators (NAMs) of Metabotropic Glutamate Receptor 5 (mGlu₅): From an Artificial Neural Network Virtual Screen to an In Vivo Tool Compound

Ralf Mueller, Eric S. Dawson, Jens Meiler et al. · ChemMedChem · 2012 · 45 citations