Takanobu Kuroita

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lodoe Lama, Carolina Adura, Wei Xie et al. · Nature Communications · 2019 · 283 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

In Vitro Antagonistic Properties of a New Angiotensin Type 1 Receptor Blocker, Azilsartan, in Receptor Binding and Function Studies

Mami Ojima, Hideki Igata, Masayuki Tanaka et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 150 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice

Toshiya Nishi, Shinichi Kondo, Maki Miyamoto et al. · Scientific Reports · 2020 · 76 citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Antihypertensive, insulin-sensitising and renoprotective effects of a novel, potent and long-acting angiotensin II type 1 receptor blocker, azilsartan medoxomil, in rat and dog models

Keiji Kusumoto, Hideki Igata, Mami Ojima et al. · European Journal of Pharmacology · 2011 · 53 citations

Medicine, Pharmacology, Pharmacotherapy +17

Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H)

Tatsuki Koike, Masato Yoshikawa, Haruhi Kamisaki Ando et al. · Journal of Medicinal Chemistry · 2021 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17