Concepedia

Toshiya Nishi

TN

Statistics

Publications

14

Citations

469

H-Index

13

Active since

1979

Affiliations

Takeda (Japan)(Current)

Takeda (United States)

Ovid Therapeutics (United States)

The University of Tokyo

University of Washington

Toshiya Nishi is an author at Takeda (Japan) specializing in medicine, virology, and pharmacology.

ORCID

Top concepts

Publications per year

1979–2022

14

Publications

14

Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice

Toshiya Nishi, Shinichi Kondo, Maki Miyamoto et al. · Scientific Reports · 2020 · 75 citations · Full text

Analysis of Binding Sites for the New Small-Molecule CCR5 Antagonist TAK-220 on Human CCR5

Masao Nishikawa, Katsunori Takashima, Toshiya Nishi et al. · Antimicrobial Agents and Chemotherapy · 2005 · 61 citations · Full text

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Soticlestat, a novel cholesterol 24‐hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice

Nicole A. Hawkins, Manuel Jurado, Tyler Thaxton et al. · Epilepsia · 2021 · 61 citations · Full text

Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H)

Tatsuki Koike, Masato Yoshikawa, Haruhi Kamisaki Ando et al. · Journal of Medicinal Chemistry · 2021 · 45 citations · Full text

Preferential enhancement of GluN2B-containing native NMDA receptors by the endogenous modulator 24S-hydroxycholesterol in hippocampal neurons

Xiaofei Wei, Toshiya Nishi, Shinichi Kondou et al. · Neuropharmacology · 2018 · 38 citations

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