Karin Conde‐Knape

Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans

Brian Finan, Tao Ma, Nickki Ottaway et al. · Science Translational Medicine · 2013 · 675 citations

Medicine, Pharmacokinetics, Pharmacology +16

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

Brian Finan, Bin Yang, Nickki Ottaway et al. · Nature Medicine · 2014 · 627 citations · Full text

Life Sciences, Biochemistry, Endocrinology +12

Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Martha J. Kelly, Sherrie Pietranico-Cole, J. Douglas Larigan et al. · Journal of Medicinal Chemistry · 2014 · 215 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture

Jiangming Sun, Pratibha Singh, Annelie Shami et al. · Journal of the American College of Cardiology · 2023 · 102 citations · Full text

Life Sciences, Cardiology, Molecular Biology +10

Systemic bile acid sensing by <scp>G</scp> protein‐coupled bile acid receptor 1 (<scp>GPBAR1</scp>) promotes <scp>PYY</scp> and <scp>GLP</scp>‐1 release

Christoph Ullmer, Rubén Alvarez Sánchez, Urs Sprecher et al. · British Journal of Pharmacology · 2013 · 87 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17