Rubén Alvarez Sánchez

Systemic bile acid sensing by <scp>G</scp> protein‐coupled bile acid receptor 1 (<scp>GPBAR1</scp>) promotes <scp>PYY</scp> and <scp>GLP</scp>‐1 release

Christoph Ullmer, Rubén Alvarez Sánchez, Urs Sprecher et al. · British Journal of Pharmacology · 2013 · 86 citations · Full text

Discovery of Highly Selective and Orally Active Lysophosphatidic Acid Receptor-1 Antagonists with Potent Activity on Human Lung Fibroblasts

Yimin Qian, Matthew J. Hamilton, Achyutharao Sidduri et al. · Journal of Medicinal Chemistry · 2012 · 54 citations · Full text

Immunology, Pharmacotherapy, Lpa Stimulation +20

Discovery of Highly Selective Brain-Penetrant Vasopressin 1a Antagonists for the Potential Treatment of Autism via a Chemogenomic and Scaffold Hopping Approach

Hasane Ratni, Mark Rogers‐Evans, Caterina Bissantz et al. · Journal of Medicinal Chemistry · 2015 · 49 citations · Full text

Engineering, Scaffold Hopping Exercise, Receptor Antagonist 38 +17

Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds

Hans Hilpert, Harald Mauser, Roland Humm et al. · Journal of Medicinal Chemistry · 2013 · 46 citations · Full text

Promising Scaffold, Medicinal Chemistry, Pharmaceutical Science +12

Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes

Eric Kitas, Peter J. Mohr, Bernd Kuhn et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 29 citations · Full text

Diabetes Management, Type-2 Diabetes, Biochemistry +9