Julia Japtok

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

Marcel Naumann, Arun Pal, Anand Goswami et al. · Nature Communications · 2018 · 285 citations · Full text

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

Lara Marrone, Ina Poser, Ian Casci et al. · Stem Cell Reports · 2018 · 103 citations · Full text

Cell Autophagy, Autoantibody Production, Autophagy +8

Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging

Julia Japtok, Xenia Lojewski, Marcel Naumann et al. · Neurobiology of Disease · 2015 · 66 citations · Full text

Neurodegenerative Diseases, Stepwise Acquirement, Alzheimer's Disease +11

FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration

Barbara Szewczyk, René Günther, Julia Japtok et al. · Cell Reports · 2023 · 60 citations · Full text

Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations

Franziska Bursch, Norman Kalmbach, Maximilian Naujock et al. · Human Molecular Genetics · 2019 · 54 citations