Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Caroline Vance, Boris Rogelj, Tibor Hortobágyi et al. · Science · 2009 · 2.6K citations · Full text

Life Sciences, Genetics, Neurology +17

Mutations in the <i>FUS/TLS</i> Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

Thomas J. Kwiatkowski, Daryl A. Bosco, Aurélie Leclerc et al. · Science · 2009 · 2.6K citations

Life Sciences, Genetics, Molecular Genetics +14

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

Yichen Shi, Peter Kirwan, James Smith et al. · Nature Neuroscience · 2012 · 838 citations

Life Sciences, Neurobiology, Neuroscience +16

ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import

Dorothee Dormann, Ramona Rodde, Dieter Edbauer et al. · The EMBO Journal · 2010 · 836 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

A new subtype of frontotemporal lobar degeneration with FUS pathology

Manuela Neumann, Rosa Rademakers, Sigrun Roeber et al. · Brain · 2009 · 716 citations · Full text

Life Sciences, Neurology, Pathology +16