James Smith

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

Yichen Shi, Peter Kirwan, James Smith et al. · Nature Neuroscience · 2012 · 828 citations

Synaptic Plasticity, Induced Pluripotent Stem Cell, Developmental Biology +14

A role for Dicer in immune regulation

Bradley S. Cobb, Arnulf Hertweck, James Smith et al. · The Journal of Experimental Medicine · 2006 · 515 citations · Full text

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

João D. Pereira, Stephen N. Sansom, James Smith et al. · Proceedings of the National Academy of Sciences · 2010 · 472 citations · Full text

Histone Modifications, Progenitor Cells, Epigenetic Change +21

The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis

Stephen N. Sansom, Dean Griffiths, Andrea Faedo et al. · PLoS Genetics · 2009 · 409 citations · Full text

Transcription Factor Pax6, Brain Development, Adult Stem Cell +18

A Human Stem Cell Model of Early Alzheimer’s Disease Pathology in Down Syndrome

Yichen Shi, Peter Kirwan, James Smith et al. · Science Translational Medicine · 2012 · 305 citations · Full text

Early Alzheimer ’, Stem Cell Biology, Amyloid Precursor Protein +19