Ian Casci

RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations

J. Gavin Daigle, Nicholas A. Lanson, Rebecca B. Smith et al. · Human Molecular Genetics · 2012 · 207 citations · Full text

Rna Processing, Neurodegenerative Diseases, Transcriptional Regulation +15

Copy number variants of schizophrenia susceptibility loci are associated with a spectrum of speech and developmental delays and behavior problems

Trilochan Sahoo, Aaron Theisen, Jill A. Rosenfeld et al. · Genetics in Medicine · 2011 · 118 citations

Psychiatry, Risk Prediction, Psychotic Disorder +11

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

Lara Marrone, Ina Poser, Ian Casci et al. · Stem Cell Reports · 2018 · 103 citations · Full text

Cell Autophagy, Autoantibody Production, Autophagy +8

Protein Arginine Methyltransferase 1 and 8 Interact with FUS to Modify Its Sub-Cellular Distribution and Toxicity In Vitro and In Vivo

Chiara Scaramuzzino, John Monaghan, Carmelo Milioto et al. · PLoS ONE · 2013 · 102 citations · Full text

Epigenetic Change, Molecular Biology, Epigenetics +18

Protein Arginine Methyltransferase 6 Enhances Polyglutamine-Expanded Androgen Receptor Function and Toxicity in Spinal and Bulbar Muscular Atrophy

Chiara Scaramuzzino, Ian Casci, Sara Parodi et al. · Neuron · 2015 · 101 citations · Full text