Aiwen Li

2-Amino-1,3-thiazol-4(5<i>H</i>)-ones as Potent and Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors: Enzyme−Ligand Co-Crystal Structure and Demonstration of Pharmacodynamic Effects in C57Bl/6 Mice

L. E. B. Johansson, Christopher Fotsch, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2008 · 49 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Enzyme−ligand Co-crystal Structure +17

Target-Directed Enediynes:  Designed Estramycins

Graham B. Jones, George W. Hynd, Justin M. Wright et al. · The Journal of Organic Chemistry · 2001 · 44 citations

The discovery of 2-anilinothiazolones as 11β-HSD1 inhibitors

Chester Yuan, David J. St. Jean, Qingyian Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 41 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Drug Target +7

Oxa-Enediynes:  Probing the Electronic and Stereoelectronic Contributions to the Bergman Cycloaromatization

Graham B. Jones, Justin M. Wright, George W. Hynd et al. · The Journal of Organic Chemistry · 2002 · 29 citations

Engineering, Heterocyclic, Biochemistry +13

Potent Nonpeptide Antagonists of the Bradykinin B1 Receptor:  Structure−Activity Relationship Studies with Novel Diaminochroman Carboxamides

Kaustav Biswas, Aiwen Li, Jian Jeffrey Chen et al. · Journal of Medicinal Chemistry · 2007 · 26 citations · Full text