Todd W. Rockway

Mutations Conferring Resistance to a Hepatitis C Virus (HCV) RNA-Dependent RNA Polymerase Inhibitor Alone or in Combination with an HCV Serine Protease Inhibitor In Vitro

Hongmei Mo, Liangjun Lu, Ron Pithawalla et al. · Antimicrobial Agents and Chemotherapy · 2005 · 120 citations · Full text

Viral Replication, Hepatitis C Virus, Viral Hepatitis +12

Identification of Novel Inhibitors of Urokinase via NMR-Based Screening

Philip J. Hajduk, Steven A. Boyd, David G. Nettesheim et al. · Journal of Medicinal Chemistry · 2000 · 79 citations · Full text

Medicinal Chemistry, Drug Target, Pharmaceutical Science +15

Pyridone-Containing farnesyltransferase inhibitors: synthesis and biological evaluation

Lisa Hasvold, Weibo Wang, Stephen L. Gwaltney et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 73 citations · Full text

Medicinal Chemistry, Pyridone-containing Farnesyltransferase Inhibitors, Medicine +5

Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of <i>N</i>-Phenyl Amide 6-Substitution

Michael Wendt, Todd W. Rockway, Andrew Geyer et al. · Journal of Medicinal Chemistry · 2003 · 66 citations · Full text

Structure-directed discovery of potent non-peptidic inhibitors of human urokinase that access a novel binding subsite

V. Nienaber, Donald J. Davidson, Rohinton Edalji et al. · Structure · 2000 · 56 citations · Full text

Novel Binding Subsite, Drug Target, Biochemistry +8