LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation

Matthew Simon, Michael Van Meter, Julia Ablaeva, +17

Cell Metabolism

InflammationLifespan ExtensionAutoimmune DiseaseImmune Cell DevelopmentImmunology +9

Slow TCA flux and ATP production in primary solid tumours but not metastases

Caroline Bartman, Daniel Weilandt, Yihui Shen, +25

Nature

Tumor BiologyTumoral PathologySlow Tca FluxMalignant DiseaseMedicine +8

Restoration of energy homeostasis by SIRT6 extends healthy lifespan

Asael Roichman, Sivan Elhanati, Miguel A. Aon, +20

Nature Communications

Gut bacterial nutrient preferences quantified in vivo

Xianfeng Zeng, Xi Xing, Meera Gupta, +10

Cell

NutritionDysbiosisGut MicrobiologyMicrobiologyGut Barrier +4

L-Lactate Promotes Adult Hippocampal Neurogenesis

Yaeli Lev-Vachnish, Sharon Cadury, Aviva Rotter-Maskowitz, +7

Frontiers in Neuroscience

Brain DevelopmentDevelopmental Cognitive NeuroscienceSocial SciencesFitness StandardsAdult Neurogenesis +18

Multiple Regulatory Layers of SREBP1/2 by SIRT6

Sivan Elhanati, Yariv Kanfi, Alexander Varvak, +5

Cell Reports

SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα

Shoshana Naiman, Frank K. Huynh, Reuven Gil, +18

Cell Reports

SIRT6 Overexpression Improves Various Aspects of Mouse Healthspan

Asael Roichman, Yariv Kanfi, Renana Glazz, +8

The Journals of Gerontology Series A

Anti-agingAgingCell DeathCaloric RestrictionOld Moses Mice +19

Telomeres and Longevity: A Cause or an Effect?

Huda Adwan Shekhidem, Lital Sharvit, Eva Leman, +8

International Journal of Molecular Sciences

Systematic identification and characterization of genes in the regulation and biogenesis of photosynthetic machinery

Moshe Kafri, Weronika Patena, Lance Martin, +14

Cell

Photosynthetic MachineryPhotorespirationGeneticsMaster Regulator Pmr1Molecular Biology +16