High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat

Xiao Tian, Jorge Azpurua, Christopher Hine, +7

Nature

Tumor BiologyCancer ResistanceHigh-molecular-mass HyaluronanMalignant DiseaseNaked Mole Rat +8

LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation

Matthew Simon, Michael Van Meter, Julia Ablaeva, +17

Cell Metabolism

InflammationLifespan ExtensionAutoimmune DiseaseImmune Cell DevelopmentImmunology +9

Universal DNA methylation age across mammalian tissues

Ake T. Lu, Zhe Fei, Amin Haghani, +184

Nature Aging

Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism

Vera Gorbunova, Christopher Hine, Xiao Tian, +4

Proceedings of the National Academy of Sciences

ApoptosisImmunologyPathologyCell DeathImmune System +19

Universal DNA methylation age across mammalian tissues

Aimei Lu, Zhe Fei, Amin Haghani, +184

AgingEpigenetic ChangeGeneticsDna MethylationMolecular Genetics +14

Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice

Zhihui Zhang, Xiao Tian, J. Yuyang Lu, +13

Nature

Tissue EngineeringInflammationNaked Mole-rat Has2ImmunologyWound Healing +4

Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties

Masaki Takasugi, Denis Firsanov, Gregory Tombline, +4

Nature Communications

DNA methylation clocks tick in naked mole rats but queens age more slowly than nonbreeders

Steve Horvath, Amin Haghani, Nicholas Macoretta, +13

Nature Aging

Transposon-triggered innate immune response confers cancer resistance to the blind mole rat

Yang Zhao, Ena Oreskovic, Quanwei Zhang, +15

Nature Immunology

Cancer ImmunosurveillanceBlind Mole RatInnate Immune SystemImmunologyImmunoediting +8

Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming

Li Tan, Zhonghe Ke, Gregory Tombline, +13

Stem Cell Reports